Abrogation of Attenuated Lentivirus‐Induced Protection in Rhesus Macaques by Administration of Depo‐Provera before Intravaginal Challenge with Simian Immunodeficiency Virus mac239
نویسندگان
چکیده
منابع مشابه
Abrogation of attenuated lentivirus-induced protection in rhesus macaques by administration of depo-provera before intravaginal challenge with simian immunodeficiency virus mac239.
In nonhuman primate models of acquired immunodeficiency syndrome, live attenuated lentiviruses provide the most reliable protection from systemic and mucosal challenge with pathogenic simian immunodeficiency virus (SIV). Although live attenuated lentiviruses may never be used in humans because of safety concerns, understanding the nature of the protective immune mechanisms induced by live atten...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2004
ISSN: 0022-1899,1537-6613
DOI: 10.1086/424600